# service exim restart
Shutting down clamd:                                       [FAILED]
Shutting down exim:                                        [FAILED]
Shutting down spamd:                                       [FAILED]

# service exim status
exim dead but subsys locked

There may be 2 issues to check.

-The presence of /etc/eximdisable, just move this file to eximdisable-bak and restart exim

# mv /etc/eximdisable /etc/eximdisable-bak

# service exim restart
Shutting down clamd:                                       [FAILED]
Shutting down exim:                                        [FAILED]
Shutting down spamd:                                       [  OK  ]
Starting clamd:                                            [  OK  ]
Starting exim:                                             [  OK  ]
0 processes (antirelayd) sent signal 9
/usr/local/cpanel/scripts/update_sa_rules: running in background

-The server being out of disk space and/or inodes, use ‘df -h’ and ‘df -i’ to confirm.